Comparing the Diagnostic Outcomes of Staining Various Breast Lesions with Either Anti-CK 5/6 or Anti-CK 5

Diagnostic application of CK-MB mass determination.

Recent advances in analytic techniques have increased the diagnostic value of creatine kinase MB (CK-MB), enabling earlier and more sensitive results. The CK-MB mass immunoassays, that utilise the monoclonal anti-CK-MB in conjunction with anti-M or anti-B antibodies, are able to measure accurately small changes during the early hours after myocardial infarction (MI). CK-MB has two main limitati...

Limited diagnostic value of CK-MB.

Macro-CK and CK-BB Contributing to Sham CK-MB Elevation

A 65-year-old man in whom an inferior vena cava filter had been implanted for deep vein thrombosis was admitted to the cardiology department due to appetite loss and lumbago. Laboratory data showed increased total creatinine kinase (CK, 796 U/L, Picture 1, left) and CK-MB (1,213 U/ L), which exceeded the total CK value. Electrophoresis showed, in addition to an increase in CK-BB, a peak that mi...

CK Gurung

A novel platform for detection of CK+ and CK- CTCs.

UNLABELLED Metastasis is a complex, multistep process that begins with the epithelial-mesenchymal transition (EMT). Circulating tumor cells (CTC) are believed to have undergone EMT and thus lack or express low levels of epithelial markers commonly used for enrichment and/or detection of such cells. However, most current CTC detection methods target only EpCAM and/or cytokeratin (CK) to enrich e...

Circulating CK-MB and CK-BB isoenzymes after prostate resection.

We studied the effect of prostate resection on serum creatine kinase (EC 2.7.3.2) and lactate dehydrogenase (EC 1.1.1.27) isoenzymes in 22 patients. Two hours after their operations, two-thirds of these patients had increased total creatine kinase activity. The MB isoenzyme was demonstrated in sera of 66% of the patients and the BB isoenzyme in 76%. MB content varied from 1 to 7% of total creat...